marfan syndrome life expectancy reddit
Marfan syndrome is a genetic disorder that affects the bodys ability to make healthy connective tissue which supports the bones muscles organs and tissues in your body. Your case may be mild and youve been checked by a doctor so maybe it is unlikely to shorten your life.
Marfan Syndrome Circulation Cardiovascular Genetics
Organs eyes heart and blood vessels nervous system and lungs.
. Long thin hands and feet. The average life expectancy of a person with Marfan syndrome is 45 years if it is untreated. The leading cause of death in Marfan syndrome is heart disease.
The average life expectancy of those affected by Marfans is about 70. Despite the high risk for Marfan related cardiovascular problems the average life expectancy of those with Marfan syndrome is nearly 70 years. I have Marfan Syndrome.
Posting this as a separate comment because I just looked it up. The most common problem associated with Marfan are aortic aneurysms which can then lead to aortic dissection a tear in the wall of the heart. The condition can affect different areas of the body including.
This poor survival was demonstrated in a series of 257 patients with the Marfan syndrome. Back when I was 16 I had an echo done which said my aortic root was 256 cm and that my ascending aorta was 23 cm. The average age of death was 32.
Reasons for this dramatic increase may include 1 an overall improvement in population life expectancy 2 benefits arising from cardiovascular surgery and 3 greater proportion of milder cases due to increased frequency of diagnosis. I am 64 140 lbs. With me being 24 Im thinking thats obviously not great.
The life expectancy has increased a lot. Basic and clinical research leading to better diagnosis and management. This is a pretty good site to answer some common non-technical questions you may have I directed it to the life expectancy question.
The role of a chemical messenger called transforming growth factor-beta TGF-β. My grandpa lived to be 62. The life expectancy in this syndrome has increased to greater than 25 since 1972.
Its estimated that around 1 in 5000 people have this condition so it is rare but not so rare that doctors. The survival of untreated patients with Marfan syndrome is reduced by about one third with death occurring at an average age of 30-40 years. Nowadays people with Marfan syndrome live until age 70 which is comparable to the average life expectancy of the general population.
3540 years is the average for someone who doesnt follow guidelines such as not exercising riding roller coasters and things like that but someone who does what their doctors tell them can live an average lifespan. This is a life threatening problem and the most common cause of death in people with Marfan. One in 10 patients may have a high risk of death with this syndrome due to heart problems.
Factors that cause problems of the heart and blood vessels. 50 median cumulative survival in the total cohort n 206 was 53 years for males and 72 years for females. Survival curves were generated and data were analyzed.
Hey everyone for context I have basically every single physical symptom of marfans besides visual difficulties. Average life expectancy - 60 years old. The process resulting in skeletal problems.
And am rail thin have an inverted chest and a life expectancy of between 30-45 years. A total of 206 patients with Marfan syndrome were ascertained throughout genetic clinics in Wales and Scotland during the period 19701990. The median cumulative probability of survival was 61 years significantly increased compared with the median survival of 47 years for patients with Marfan syndrome determined 30 years ago P.
Marfan syndrome is a familial genetic hereditary condition affecting connective tissue of the body. But then Ive also read that people with Marfans have a normal life expectancy so I dont know what to think but Im leaning towards thinking negatively. A detailed family history medical history.
However with proper care there can be normal life expectancy. Bones ligaments tendons and cartilage. And from what Ive understood after primary operation the expected survival rate is around 10 years.
Marfan Syndrome is a genetic disorder that is carried on gene FBN1 which is responsible for encoding fibrillin-1 and fibrillin-2. I think generally Marfans means lower life expectancy. Posted by u.
Symptoms and characteristics include an arched palate roof of the mouth scoliosis and flat feet. The figure of 30 years is somewhat old and was represents untreated cases. A newly recognized syndrome of Marfanoid habitus.
Cardiovascular and nervous system. Despite the high risk for Marfan related cardiovascular problems the average life expectancy of those with Marfan syndrome is nearly 70 years. The average age at death for the 72 deceased patients was 32 years.
Genetic testing and counseling are available for this syndrome. Am J Med Genet. With proper treatment they can live up to half the time a normal person would or longer.
And a specific pattern of language and learning disabilities. However there are no guarantees and having Marfan syndrome does not mean you might not acquire other conditions that are common in the aging population. Marfan Syndrome Life Expectancy 1972 median survival 48 years 1993 median survival 72 years Why.
Cardiac problems led to 52 of the 56. Advances in the management of the cardiovascular manifestations of this syndrome have led to a significant decrease in the death rate that is. I always thought I had Marfans Syndrome.
Scientists are investigating several aspects of Marfan syndrome such as for example. Mean age at death was 453 165 years. People who are properly diagnosed adapt their lifestyle and receive appropriate medical and surgical management can live a normal life span into the 70s.
My uncle is almost 60 and doing fine. Both children and adults can live Marfan syndrome as long as they engage in appropriate medical care receive accurate information from their doctor and social support to make living with the disease more manageable. There were 45 deaths representing 22 of the cohort.
Thats the killer in Marfans the aortic root swells up to three times the normal size and blood has a possibility of going backwards in the heart causing death. Head over to rmovies for to hear our Reddit. In conclusion life expectancy for patients with the Marfan syndrome has increased 25 since 1972.
Problems with the eyes.
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